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However, conditional knockdown of Mfn1/2 in mouse cardiomyocytes results in increased mitochondrial dysfunction and cardiac hypertrophy due to impaired mitophagy [40]

Dr Ko Ho, director of the Gerald Choa Neuroscience Institute and an associate professor of CU Medicine, said the team made the discovery while pursuing effective interventions targeting ageing-related biological changes

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For individuals managing weight, this contributes to increased feelings of fullness and satiety, helping to reduce overall food intake